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The inheritance of enzyme variants of glutamic-oxaloacetic transaminase in Paragonimus ohirai

Published online by Cambridge University Press:  06 April 2009

Takeshi Agatsuma  and
Shigehisa Habe
Takeshi Agatsuma
Affiliation:
Department of Parasitology, Kochi Medical School, Oko, Nankoku 781-51 (Kochi), Japan
Shigehisa Habe
Affiliation:
Department of Parasitology, School of Medicine, Fukuoka University, Fukuoka 814-01, Japan
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Summary

Lung flukes, Paragonimus ohirai, from Kinosaki, Japan, characterized by 3 electrophoretic variants, FF, FS and SS, of glutamic-oxaloacetic transaminase (GOT: EC 2.6.1.1) were crossed in the laboratory. In the case of a cross between FS and SS, a parent, FS, produced 9 SS and 16 FS clones in the offspring, numbers not significantly different from that expected (1:1) from Mendelian inheritance. From the other cross FS × FF, 20 clones originating from the respective 20 miracidia were obtained from a parent FS. The phenotype segregation ratio was 6 FF and 14 FS, which is not significantly different from Mendelian inheritance expectation. Only 3 clones were obtained from the other parent FF, but these segregated in a ratio of 2 FS: 1 FF. These breeding data indicate that the GOT isozymes of P. ohirai are controlled by 2 codominant alleles, GotF and Gots at a single locus whose products aggregate randomly, forming a dimer.

Type
Research Article
Information
Parasitology , Volume 91 , Issue 3 , December 1985 , pp. 483 - 488
Copyright
Copyright © Cambridge University Press 1985

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References

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