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Sinonasal cancer: an overview of the emerging subtypes

Published online by Cambridge University Press:  12 March 2020

J S Virk ,
J Chan ,
L Dimitrov ,
A Williamson ,
A Sandison ,
J Weir  and
P Clarke
J S Virk
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
J Chan
Affiliation:
Barts and the London School of Medicine and Dentistry, London, UK
L Dimitrov*
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
A Williamson
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
A Sandison
Affiliation:
Histopathology Department, Guy's and St Thomas’ Hospital, London, UK
J Weir
Affiliation:
Department of Histopathology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
P Clarke
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK
*
Author for correspondence: Miss Lilia Dimitrov, ENT Department, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK E-mail: lilygdimitrov@gmail.com
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Abstract

Background

Advances in immunohistochemistry have spearheaded major developments in our understanding and classification of sinonasal tumours. In the last decade, several new distinct histopathological entities of sinonasal cancer have been characterised.

Objectives

This review aims to provide a clinical update of the major emerging subtypes for the ENT surgeon and an overview of the management strategies available for this heterogeneous group of pathologies.

Conclusion

Although rare, knowledge of sinonasal neoplasm subtypes has implications for prognosis, treatment strategies and the development of novel therapeutic targets.

Keywords

Head And Neck NeoplasmsParanasal Sinus NeoplasmsImmunohistochemistry
Type
Review Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 3 , March 2020 , pp. 191 - 196
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Miss L Dimitrov takes responsibility for the integrity of the content of the paper

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