Original articleDemonstration of feasibility of automated osteoblastic line culture in space flight
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Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission – The SPHEROIDS project
2017, BiomaterialsCitation Excerpt :Beside the 3D round aggregates called spheroids, tube-like structures could be distinguished. Many biological experiments with plants, small animals or mammalian cells have been conducted in space on the ISS [17-22]. There are some articles describing the concept of EUs for use on board the ISS [23-25], however only a few publications have reported the biocompatibility test results of the materials in use [11,20].
Effects of hypergravity on adipose-derived stem cell morphology, mechanical property and proliferation
2015, Biochemical and Biophysical Research CommunicationsCitation Excerpt :In contrary, Gebken et al. (1999) found a slight reduction in the number of osteoblast like cell after hypergravity of 13 g [14]. Also, no significant changes observed in proliferation of cells underwent spaceflight test in other studies [27,28]. The differences in results obtained by different researchers can be justified due to the differences in cell type, method of gravity exposure, level of gravity from 2 g to 2000 g, and hypergravity exposure time from some minutes to days, hypergravity exposure methods, and even the interval between the exposure periods.
Focal contacts organization in osteoblastic cells under microgravity and cyclic deformation conditions
2003, Advances in Space ResearchOsteogenesis in altered gravity
2002, Advances in Space Biology and MedicinePhysiological effects of microgravity on osteoblast morphology and cell biology
2002, Advances in Space Biology and Medicine