Synthesis, antimicrobial activity and binding properties of calix[4]arene based vancomycin mimics

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Abstract

Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D-or L-alanine units and diethylentriamine segment.

References and Notes (13)

  • ChatterjeeA.N. et al.

    Biochem. Biophys. Res. Commun.

    (1966)
    PerkinsH.R.

    Biochem. J.

    (1971)
    WilliamsD.H. et al.

    J. Am. Chem. Soc.

    (1983)
  • MarraA. et al.

    Angew. Chem.

    (1994)
    MarraA. et al.

    Angew. Chem. Int. Ed. Engl.

    (1994)
  • WilliamsD.H. et al.

    Chem. Tech.

    (1996)
    ReynoldsP.E.

    Eur. J. Clin. Microbiol. Infect. Dis.

    (1989)
  • WoodfordN. et al.

    Clinical Microbiology Review

    (1995)
  • WalshC. et al.

    Chemistry and Biology

    (1996)
    ArthurM. et al.

    J. Bacteriol.

    (1992)
    Billot-KleinD. et al.

    J. Bacteriol.

    (1994)
There are more references available in the full text version of this article.

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Present address: Istituto di Chimica Farmaceutica, Università di Urbino, Piazza Rinascimento 6, Urbino 61029, Italy.

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