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Analysis of the seasonal variation of schizophrenic births using a Kolmogorov-Smirnov type statistic

Published online by Cambridge University Press:  16 April 2020

H Verdoux
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux-2, Centre Carreire, 121 rue de la Béchade, 33076Bordeaux cedex, France
N Takei
Affiliation:
Department of Psychological Medicine, Institute of Psychiatry and King's College Hospital, De Crespigny Park, London SE5 8AF, UK Division of Adult Mental Health, National Institute of Mental Health, 1-7-3 Kohnodai, Chiba272, Japan
R Cassou de Saint-Mathurin
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux-2, Centre Carreire, 121 rue de la Béchade, 33076Bordeaux cedex, France
M Bourgeois
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux-2, Centre Carreire, 121 rue de la Béchade, 33076Bordeaux cedex, France
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Summary

Previous studies have shown that schizophrenic patients are more likely to be born in winter or early spring months than the general population. Data on 4,207 patients with a hospital diagnosis of schizophrenia were obtained from a mailed survey to public departments of adult psychiatry in metropolitan France. For each year from 1900 to 1965, the expected monthly number of schizophrenic births was calculated and any seasonal variation of live births in the general population was taken into account. Cumulative distributions of the observed and expected number of schizophrenic births were compared using a Kolmogorov-Smirnov type statistic. The seasonal distribution of schizophrenic births was significantly different from that of the general population (P < 0.01). An excess of schizophrenic births was found in the first half of the year, with a peak in April (+ 13%).

Type
Original article
Copyright
Copyright © Elsevier, Paris 1997

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References

d'Amato, TDalery, JLRochet, TTerra, JLMarie-Cardine, MSaisons de naissance et psychiatrie. Étude rétrospective d'une population hospitalière. Encéphale 1991; 17: 6771Google Scholar
Bourgeois, MCassou de Saint-Mathurin, RVerdoux, HEllison, WEnquête sur les variations saisonnières des naissances des schizophrènes. Ann Med Psychol 1990; 148: 425438Google Scholar
Bourin, MVenisse, JLLecuyer, FRésultats d'une enquête sur l'utilisation en psychiatrie des neuroleptiques à action prolongée. Encéphale 1990; 16: 363369Google Scholar
Boyd, JHPulver, AEStewart, WSeason of birth: schizophrenia and bipolar disorder. Schizophr Bull 1986; 12: 173186CrossRefGoogle ScholarPubMed
Bradbury, TNMiller, GASeason of birth in schizophrenia: a review of evidence, methodology, and etiology. Psychol Bull 1985; 98: 569594CrossRefGoogle ScholarPubMed
Castle, DJMurray, RMThe neurodevelopmental basis of sex differences in schizophrenia. Psychol Med 1991; 21: 565575CrossRefGoogle Scholar
Denicoff, KDMeglathery, SBPost, RMTandeciarz, SIEfficacy of carbamazepine compared with other agents: a clinical practice survey. J Clin Psychiatry 1994; 55: 7076Google ScholarPubMed
Freedman, LSThe use of a Kolmogorov-Smimov type statistic in testing hypotheses about seasonal variation. J Epidemiol Community Health 1979; 33: 223228CrossRefGoogle Scholar
O'Hare, AWalsh, DTorrey, FSeasonality and schizophrenic births in Ireland. Br J Psychiatry 1980; 137: 7477CrossRefGoogle ScholarPubMed
Lewis, MSAge incidence and schizophrenia. Part I. The season of birth controversy. Schizophr Bull 1989; 15: 5973CrossRefGoogle ScholarPubMed
Lewis, MSGriffin, TAAn explanation for the season of birth effect in schizophrenia and certain other diseases. Psychol Bull 1981; 89: 589596CrossRefGoogle ScholarPubMed
McGrath, JWehlam, JPemberton, MMonths of birth, hemisphere of birth and schizophrenia. Br J Psychiatry 1995; 167: 783785CrossRefGoogle Scholar
Murray, RMNeurodevelopmental schizophrenia: the rediscovery of dementia praecox Br J Psychiatry 1994 165 suppl 25 612CrossRefGoogle Scholar
Pull, CPichot, POverall, JA statistical model of psychiatric diagnostic pratices in France. Compr Psychiatry 1979; 20: 2739CrossRefGoogle Scholar
Pulver, AEMoorman, CCBrown, CHAge incidence artifacts do not account for the season of birth effect in schizophrenia. Schizophr Bull 1990; 16: 1315CrossRefGoogle ScholarPubMed
O'Callaghan, EGibson, TCoholan, HA, et al.Season of birth in schizophrenia. Evidence for a confinement of an excess of winter births to patients without a family history of mental disorder. Br J Psychiatry 1991; 158: 764769CrossRefGoogle ScholarPubMed
Shimura, MNakamura, IMiura, TSeason of birth of schizophrenics in Tokyo, Japan. Acta Psychiatr Scand 1977; 555: 225232CrossRefGoogle Scholar
Verdoux, HGonzales, BTakei, NBourgeois, MA survey of prescribing practice of antipsychotic maintenance treatment for manic-depressive outpatients. J Affective Disord 1996; 38: 8187CrossRefGoogle ScholarPubMed
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