Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume 21, Issue 4, May 1997, Pages 697-706
Experimental laboratory studyEffects of kawain and dihydromethysticin on field potential changes in the hippocampus
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Cited by (42)
Anesthetic considerations of the herbal, kava
2004, Journal of Clinical AnesthesiaPost-insult exposure to (±) kavain potentiates N-methyl-D-aspartate toxicity in the developing hippocampus
2002, Brain ResearchCitation Excerpt :Kavain has been reported to produce rapid inhibition of voltage-sensitive Na+ channel function in a synaptosomal preparation [10] and to reduce veratridine-induced striatal glutamate release in vivo [9]. Further, kavain and dihydromethisticin were reported to reduce field potential changes produced by Mg2+ depletion and subsequent over activation of N-methyl-d-aspartate (NMDA)-type glutamate receptors in the guinea pig hippocampus [29]. Kavain and yangonin have also been reported to induce dopamine release in nucleus accumbens in awake, behaving rats [2], an effect related to the onset of sedation and muscle relaxation.
Kava-kava and anxiety: Growing knowledge about the efficacy and safety
2002, Life SciencesA comprehensive review on the medicinal use of Piper methysticum (Kava)
2023, Medicinal Roots and Tubers for Pharmaceutical and Commercial ApplicationsUnderstanding the mechanistic functioning of bioactive compounds in medicinal plants
2021, Medicinal and Aromatic Plants: Healthcare and Industrial Applications
Copyright © 1997 Published by Elsevier Inc.