Accuracy of clean-catch urine collection in infancy☆,☆☆
Section snippets
PATIENTS AND METHODS
After local ethics committee approval was obtained, patients younger than 24 months in whom urine culture was indicated were identified from The Royal Hospital for Sick Children, Glasgow, and its associated neonatal unit. Infants with paired urine cultures obtained by both SPA and CCU collection within a 48-hour period, in the absence of prior or intervening antibiotic therapy, were recruited.
Urine was collected by SPA with the technique described by Nelson and Peters.8 Clean-catch specimens
RESULTS
The results of both CCU and SPA cultures are shown in the Table.
Empty Cell SPA positive SPA negative CCU positive 16 2 CCU negative 2 38 Total 18 40
Of 16 cultures in which SPA and CCU were positive, Escherichia coli was identified in 14, Pseudomonas aeruginosa in 1, and Candida albicans in 1. The 2 specimens that were
DISCUSSION
Rapid and accurate diagnosis of UTI is extremely important in view of the prevalence in the febrile infant.9 However, difficulty in specimen collection and interpretation of inadequately collected specimens may contribute to the underdiagnosis and underinvestigation of UTI in childhood, both in the hospital7 and in the office environment.10 This may result in an increased risk of renal scarring,11 especially in infants with underlying abnormalities of the urinary tract. Similarly, a
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Cited by (0)
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Reprint requests: Ian J. Ramage, MBChB, MPCP(UK), MRCPCH, Renal Unit, Royal Hospital for Sick Children, Glasgow, Scotland, UK G3 8SJ.
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0022-3476/99/$8.00 + 0 9/22/102408