Prospective, randomized comparison of disposable and reusable biopsy forceps in gastrointestinal endoscopy☆,☆☆,★,★★,♢
Section snippets
MATERIALS AND METHODS
Patients undergoing routine endoscopic examination (esophagogastroduodenoscopy, colonoscopy, or flexible sigmoidoscopy) were enrolled in the study. Biopsy specimens were taken from normal-appearing stomach, duodenum, or sigmoid colon by two experienced endoscopists. Two specimens were obtained in the same region of the gastrointestinal tract with each of six different biopsy forceps. The disposable forceps were discarded after each set of specimens had been taken. The order of use of the
RESULTS
No complications associated with use of jumbo- or regular-sized forceps were observed. All biopsy forceps gave reliable specimens with no crush artifact. Four forceps failed mechanically. One disposable long-jaw forceps failed to open and close completely. One jumbo reusable and two regular reusable forceps failed to open.
The average volumes for the forceps are summarized in Figure 2.
DISCUSSION
This report prospectively compares reusable and disposable biopsy forceps of varying sizes during routine gastrointestinal endoscopy. We have demonstrated that reusable and disposable jumbo forceps yield biopsy specimens of similar depth and volume and that the specimens obtained with the jumbo forceps are double the size of specimens obtained with regular-sized forceps. However, the same depth can be achieved with regular disposable forceps as with jumbo forceps. Thus, the total volume is
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Cited by (31)
Image-guided biopsy in the esophagus through comprehensive optical frequency domain imaging and laser marking: a study in living swine
2010, Gastrointestinal EndoscopyCitation Excerpt :The anatomic depth of the thermal injuries caused by the 2-second laser exposures was measured to extend to 27.03% of the full thickness of the mucosa, with partial healing observed at day 2. Given that the histologic depth of biopsy specimens obtained by using standard forceps has been reported to extend to the muscularis mucosa,12 we anticipate that the risk to the patient undergoing this procedure will be low and not significantly greater than that of standard endoscopic practice. The overarching goal of this research is to provide endoscopists with a method for guiding biopsies to decrease the sampling errors associated with surveillance.
Update on endoscopic tissue sampling devices
2006, Gastrointestinal EndoscopyCitation Excerpt :Recently, proper endoscope reprocessing has been identified to be the most important factor in preventing biopsy forceps–related interpatient infection.44 In 2 prospective, randomized, pathologist-blinded trials there were no perceived differences in quality of specimen attained for histological diagnosis among a variety of commercially available reusable and disposable biopsy forceps.45,46 Forceps with central spikes obtain deeper biopsies than nonspiked versions.15
Disposable versus reusable biopsy forceps in GI endoscopy: A cost-minimization analysis
2003, Gastrointestinal EndoscopyAdequacy of mucosal sampling with the "two-bite" forceps technique: A prospective, randomized, blinded study
2003, Gastrointestinal EndoscopyAn observer-blinded, prospective, randomized comparison of forceps for endoscopic esophageal biopsy
2002, Gastrointestinal EndoscopyCitation Excerpt :It is widely agreed that greater size is the most important factor in determining diagnostic quality of biopsy specimens. Moreover, there is general agreement that a forceps with larger cups provides larger specimens.6-8 The use of “jumbo” forceps is an accepted method of tissue sampling, especially for surveillance in patients with Barrett's metaplasia.9
Diagnostic quality of biopsy specimens: Comparison between a conventional biopsy forceps and Multibite forceps
2001, Gastrointestinal Endoscopy
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From the Gastrointestinal and Liver Diseases Division, Department of Medicine and Department of Pathology, University of Southern California School of Medicine, Los Angeles, California.
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Reprint requests: Russell Yang, MD, PhD, USC School of Medicine, Gastrointestinal and Liver Diseases Division, Department of Medicine, 2025 Zonal Ave., Los Angeles, CA 90033.
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0016-5107/94/4006-0671$3.00 + 0
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GASTROINTESTINAL ENDOSCOPY