EditorialThe winter's tale—and toll
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Micro-inflammatory changes in asymptomatic healthy adults during bouts of respiratory tract infections in the community: Potential triggers for atherothrombotic events
2009, AtherosclerosisCitation Excerpt :Support for the role of CRP and quantitative fibrinogen in the pathogenesis of atherosclerosis comes largely from epidemiologic studies that have consistently observed an association between elevated inflammatory biomarker levels and cardiovascular events [4,5]. Cardiovascular events are known to have a seasonal pattern, generally assumed to be related to influenza epidemics and increased rates of acute infectious respiratory diseases [6,7]. In fact, influenza vaccination has been shown to be associated with a decrease in recurrent coronary events [8,9].
Seasonal variation in serum cholesterol levels may be another explanation for seasonal variation in acute myocardial infarction [1]
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