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doi:10.1016/j.yebeh.2006.08.010 
Copyright © 2006 Elsevier Inc. All rights reserved.
Subjective somnolence relates mainly to depression among patients in a tertiary care epilepsy center
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Sigmund Jenssena, 
, 
, Edward Gracelyb, Tariq Mahmoodc, Joseph I. Tracyc and Michael R. Sperlingc
Received 21 July 2006;
Abstract
Many patients with epilepsy complain of decreased energy and somnolence. There is increased awareness that comorbidity, especially depression, plays an important role in determining the quality of life for patients with epilepsy. We set out to determine how subjective somnolence is affected by depression, age, hours of sleep, sleep apnea, seizure frequency, and numbers of antiepileptic drugs and central nervous system drugs. A questionnaire and chart review were used to investigate patients in a tertiary referral center. We found that subjective somnolence was prominent and that it relates mainly to depression, less to obstructive sleep apnea, and not to the other variables. Further investigation is needed into the relationship between depression and subjective somnolence in patients with epilepsy.
Keywords: Epilepsy; Comorbidity; Somnolence; Sleep disorder; Depression; Antiepileptic medication; Adverse effect; Seizure frequency; Obstructive sleep apnea; Quality of life
Article Outline
- 1. Introduction
- 2. Methods
- 2.1. Subjects
- 2.2. Surveys
- 2.3. Chart review
- 2.4. Statistical analysis
- 3. Results
- 4. Discussion
- References
