Pediatric Case ReportBilateral Renal Cell Carcinoma in a Child
Section snippets
Case Report
In April 2004, an 8-year-old girl from Congola presented to the emergency department with a 5-day history of abdominal pain associated with nausea, vomiting, and diarrhea with rectorragia. She had no history of fever, weight loss, fatigue, urinary symptoms, or hematuria. She had no palpable abdominal mass and her blood pressure was normal.
During the initial evaluation by the pediatrician, hematologic workup and imaging were performed. Stool cultures were negative. The complete blood count
Comment
RCC accounts for 3% of all adult malignancies but is rare in the pediatric population, with an incidence of 0.1-0.3% of all neoplasms and representing 1.3-6.6% of all malignant renal tumors.1, 2, 3, 4 The incidence of RCC increases with age and the mean age at presentation is 8-9 years with no sex prevalence by most of series,1, 3, 5, 6 but a recent SEER database documented that 50% of pediatric RCCs were diagnosed after 15 years old.4
To our knowledge, this case represents the first bilateral
Conclusions
We reported the first case of bilateral RCC treated by bilateral partial nephrectomies in a child. After 80-month follow-up, the patient was recurrence-free and had normal renal function. This case raises the importance of considering nephron-sparing surgery in the pediatric population, particularly with bilateral tumors. In this population, we also have to suspect a genetic pattern with possible long-term recurrence.
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Cited by (1)
Financial Disclosure: The authors declare that they have no relevant financial interests.