Adult urologyCorrelates and prevalence of prostatitis in a large community-based cohort of older men
Section snippets
Material and methods
We conducted a cross-sectional analysis of baseline data from a prospective cohort study of 5821 men enrolled in the MrOS study. We excluded 174 men who were not white, African American, or Asian, because the number of men in other categories were too few for stratified analyses. The MrOS study is a community-based study of 5995 men from six clinical centers in the United States. To be an MrOS participant, men had to be at least 65 years old, able to walk without the assistance of another
Results
Overall, 1439 men (25%) reported a history of prostatitis. The racial prevalence distribution of prostatitis was 25% for white men, 23% for African-American men, and 17% for Asian men (P = 0.02). The prevalence of prostatitis by age category was 19% for those younger than 70 years, 25% for those 70 to 79 years, and 33% for those 80 years or older (P <0.0001).
The baseline characteristics of men with and without a history of prostatitis are compared in Table I. Men with a history of prostatitis
Comment
A self-reported history of prostatitis is associated with self-reported prostate cancer and BPH and increased severity of LUTS and associated dissatisfaction. Because of the cross-sectional nature of the data, our findings do not suggest causality but do call for additional research into the relationship of prostatitis to other diseases of the prostate. The associations among these urologic conditions may reflect increased diagnostic surveillance for other prostatic diseases once one prostatic
Conclusions
Our study results have shown that a self-reported history of prostatitis is associated with self-reported prostate cancer and BPH and increased severity of LUTS and associated dissatisfaction. Understanding the associations between prostatitis and BPH and incident prostate cancer requires additional prospective studies to determine whether symptom-driven screening would be case finding and whether effective treatment of prostatitis would lead to a reduction in prostate cancer incidence,
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2016, Prostate Cancer: Science and Clinical Practice: Second EditionLifestyle and Risk of Chronic Prostatitis/Chronic Pelvic Pain Syndrome in a Cohort of United States Male Health Professionals
2015, Journal of UrologyCitation Excerpt :As mentioned previously, the literature on CP/CPPS risk factors is generally inconclusive to date. For obesity all studies that examined body size measures as continuous variables revealed null associations.12–14 However, studies that investigated categories of overweight and obesity in relation to self-reported history of prostatitis showed protective findings7,9 and those that examined overweight/obesity in relation to CP/CPPS or pain/discomfort with ejaculation showed mixed findings.10,11,15
Prostatitis, Epididymitis, and Orchitis
2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious DiseasesThe association between metabolic syndrome and the National Institutes of health chronic prostatitis symptom index: Results from 1673 men in China
2013, UrologyCitation Excerpt :In our study, BMI was identified as a risk factor for CP/CPPS, which is not consistent with previous reports. In contrast, increased BMI was associated with decreased odds of prostatitis in African Americans; other study demonstrated that men with a BMI of >27 kg/m2 had a 0.8-fold odds (95% confidence interval, 0.7-0.9), having a history of prostatitis compared with those with BMI ≤27 kg/m227; however, Daniels et al28 reported that no association was found between a history of prostatitis and BMI. However, our study showed BMI to be closely related to NIH-CPSI, although the correlation between these variables did not seem to be linear.
This project was funded by the National Institutes of Health (NIH grants UO1 AG18197-02, UO1 AR45580-02, UO1 AR45614, UO1 AR45632, UO1 AR45647, UO1 AR45654, UO1 AR45583, and M01 RR00334). Dr. Daniels is a recipient of the Robert Wood Johnson Minority Medical Faculty Development Award and supported by grant P30-AG15272 under the Resource Centers for Minority Aging Research program funded by the National Institute on Aging, the National Institute of Nursing Research, and the National Center on Minority Health and Health Disparities, National Institutes of Health, and the Department of Defense Prostate Scholar Award.