4th Congress of the Spanish Society of TransplantationPancreas transplantationValidation of the Pancreatic Donor Risk Index in Simultaneous Pancreas-Kidney Transplantation Performed in Córdoba Hospital From 2000 to 2015
Section snippets
Methods
This was a retrospective analysis of a registry of a total of 126 SPK performed by the same surgical team in our center between the years 2000 and 2015. Patients were excluded if there were insufficient data for calculating the PDRI or loss of patient control. Eight cases were excluded from final analysis. There were no cases of donation after cardiac death.
The PDRI was calculated for all pancreas grafts through the original model proposed by Axelrod et al. We used the “Pancreas Transplant
Demographics
The mean PDRI was 1.08 (±0.31), and it ranged from 0.70 to 2.00. No case was in the highest PDRI quartile (2.12–2.86). Data from the donor cohort, logistic characteristics of the procedure, and calculated PDRI are shown in Table 1.
PDRI and Graft Survival
One-year global cumulative survival in the series was 87%. Figure 1 shows graft survival curves according to PDRI groups. One-year graft survival for lowest- to high-risk PDRI quartiles calculated by use of the Kaplan-Meier test were 92%, 88%, 85%, and 75%,
Discussion
The aim of pancreas transplantation is to improve patient survival and quality of life by minimizing the severe risks that may be associated with the procedure [8], [9]. In the current situation, in which graft demand continues to grow, a successful transplant system is based on the correct selection and distribution of available organs. In that sense, several groups have designed a model that uses data of transplant donors, to provide risks and guide organ utilization before transplantation
Conclusions
In our series, the PDRI could not be validated as a predictor of pancreatic graft outcomes after SPK.
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