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doi:10.1016/j.tetlet.2005.05.011 
Copyright © 2005 Published by Elsevier Ltd.
Selective and efficient oxidation of sulfides to sulfoxides with N-bromosuccinimide in the presence of β-cyclodextrin in water
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K. Surendraa, N. Srilakshmi Krishnavenia, V. Pavan Kumara, R. Sridhara and K. Rama Rao
, a, 
Received 28 February 2005;
revised 29 April 2005;
accepted 4 May 2005.
Available online 23 May 2005.
Abstract
A simple and highly selective oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) catalyzed by β-cyclodextrin in water has been developed. A series of sulfides were oxidized selectively at room temperature in excellent yields. This reaction proceeds without over-oxidation to sulfones under mild conditions using water as a solvent and has many advantages over the existing methodologies.
Keywords: Sulfides; Sulfoxides; Oxidation; N-bromosuccinimide; β-Cyclodextrin; Biomimetic; Water
