Cell Stem Cell
Volume 12, Issue 4, 4 April 2013, Pages 426-439
ArticleReactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog
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Graphical Abstract
Highlights
► Stab wound injury and MCAo elicit a profound stem cell response ► Noninvasive brain injury fails to elicit a stem cell response ► SHH is upregulated and required in lesion conditions with a stem cell response ► SHH transducer deletion in astrocytes reduces their proliferative response to injury
Cited by (0)
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These authors contributed equally to this work
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Present address: Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA
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Present address: Brain Institute, Federal University of Rio Grande do Norte, Natal, 59056-450, Brazil
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