Original articleTen-year changes in health-related quality of life after biliopancreatic diversion with duodenal switch☆
Section snippets
Methods
The first 51 patients who were accepted for BPDDS at Førde Central Hospital in Norway were invited to participate in a prospective cohort study. The criteria for having surgery included body mass index (BMI)≥40.0 or 35.0–39.9 kg/m2 with obesity-related co-morbidities, no active psychosis, no alcohol or drug problems, age 18 to 60 years, and failure to lose weight through other methods. Written informed consent was obtained from participants. Patients were included consecutively from 2001 to
Results
All 51 patients who were invited participated and gave written informed consent. One patient died 2 years after surgery and was excluded from the study. Seven patients were reoperated, 5 due to weight regain and 2 as a result of inadequate weight loss. Two of the 7 reoperated patients completed the 10-year follow-up. These 2 patients had a resection of the stomach 9 years after BPDDS due to weight regain after initial weight loss.
The characteristics of the patients are presented in Table 1. At
Discussion
This is, to the best of our knowledge, the first study that has prospectively evaluated 10-year changes in HRQL after BPDDS. We evaluated changes in HRQL among 35 patients with severe obesity and found statistically significant and clinically important long-term improvements from baseline. The improvements in HRQL from baseline to 2 years were dramatic, followed by moderate declines at 2 to 5 years. At 5 to 10 years the PCS score declined further, while the MCS remained stable. To date, the
Conclusion
Ten years after BPDDS. patients’ HRQL was significantly improved from preoperative values, and approximately 60% of the improvements seen at 1-year follow-up were maintained. Given the scarcity of long-term studies of HRQL after bariatric surgery, especially BPDDS, further studies should be performed to confirm these findings.
Disclosures
The authors have no financial associations that might be a conflict of interest in relation to this article.
Acknowledgments
We thank the staff that worked with the patients at Førde Central Hospital for assisting with data collection.
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This study was supported by a grant from Sogn og Fjordane University, Norway.