Research PaperMapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types
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Graphical abstract
Abbreviations
ASK1
apoptosis signal-regulating kinase 1
Cat
catalase
GSH
glutathione
GPx1
glutathione peroxidase 1
Grx
glutaredoxin
KEAP1
Kelch-like ECH-associated protein 1
NRF2
nuclear factor erythroid 2-related factor 2
Prx
typical 2-Cys peroxiredoxin
PTTRS
peroxiredoxin / thioredoxin / thioredoxin reductase system
Srx
sulfiredoxin
Trx
thioredoxin
TrxR
thioredoxin reductase
Keywords
Redox relays
Redox signaling
Thiol redox regulation
Quantitative redox biology
Systems design space methodology
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© 2018 The Authors. Published by Elsevier B.V.