Gastric carcinomaPattern of lymph node metastases and its implication in radiotherapeutic clinical target volume delineation of regional lymph node in patients with gastric carcinoma☆
Section snippets
Patients
From the total number of 1765 patients diagnosed with GC and who had undergone gastrectomy at the department of general surgical oncology in Shandong Cancer Hospital from January 2002 to December 2008, 875 patients were selected to be retrospectively studied. Eligibility criteria included: (a) patients with complete history, physical examination, and endoscopy of the upper gastrointestinal tract. Computed tomography (CT) of the chest and ultrasonography or CT of the abdomen, and/or positron
Patients and clinicopathologic features
As is shown in Table 1, there were 635 males and 240 females with a median age of 57 years (range 24–70 years), including 154 in the upper third, 209 in the middle third, 485 in the lower third, and 27 with whole GC. The maximum diameter of tumor was ⩽3.0 cm in 215 patients, 3.1–6.0 cm in 431 patients, and >6.0 cm in 229 patients. In terms of the T stage, 57 patients had T1 invasion, 134 patients T2 invasion, 191 ones T3 invasion and 493 cases T4 invasion. In terms of the macroscopic types, there
Discussion
GC is one of the most common causes of cancer death worldwide. It is characterized by a high frequency of regionalized disease with nodal metastasis. For the treatment of GC, complete tumor resection, whenever feasible, is the standard treatment. However, although the goal of each surgical attempt is to achieve an R0 resection, it is only possible for less than 50% of patients [16], [17]. The 5-year survival rate of patients with advanced loco-regional GC who have undergone curative resection
Conflict of interest statement
All authors disclose to have no financial and personal relationships with other people or organizations that could inappropriately influence their work.
Acknowledgment
The authors thank Jufu Dong and Kun Yang for the work of picture drawing.
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This study was supported in part by 30670617 and 30970861 from National Nature Science Foundation of China.