Original ArticleAlcohol, Intraocular Pressure, and Open-Angle Glaucoma: A Systematic Review and Meta-analysis
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Disclosure(s):
All authors have completed and submitted the ICMJE disclosures form.
The author(s) have made the following disclosure(s): L.R.P.: Consultant – Eyenovia, Skye Biosciences, Twenty Twenty.
J.L.W.: Consultant – Aerpio, Allergan, Editas, Maze, Regenxbio.
A.P.K.: Consultant or lecturer – Abbvie, Aerie, Allergan, Google Health, Heidelberg Novartis, Reichert, Santen, Thea.
P.J.F.: Consultant – Alphasights, GLG, Google Health, Guidepoint, PwC, Santen.
Financial support: K.V.S.: Receipt of a UCL Overseas Research Scholarship. K.V.S. and P.J.F.: Supported by grants from Fight for Sight, London (1956A) and The Desmond Foundation.
A.N.W.: Supported by the Wellcome Trust (220558/Z/20/Z).
R.N.L.: Supported by a Moorfields Eye Charity Springboard Award. L.R.P.: Supported by National Institutes of Health (NIH) EY015473, NIH EY032559, The Glaucoma Foundation (NYC), and an unrestricted Challenge Grant from Research to Prevent Blindness (NYC).
J.L.W.: Supported by NIH EY032559, NIH EY027129, NIH EY014104, NIH EY022305, NIH EY020928, NIH EY031820, an unrestricted grant from Research to Prevent Blindness (NYC), and an ARVO Foundation David Epstein Award. J.H.K.: Supported by the NIH. A.P.K.: Supported by a UK Research and Innovation Future Leaders Fellowship (Medical Research Council MR/T040912/1) and a Moorfields Eye Charity Career Development Fellowship. P.J.F.: Supported by an Unrestricted Grant from Alcon. A.P.K. and P.J.F.: A proportion of their financial support from the UK Department of Health through an award made by the National Institute for Health Research to Moorfields Eye Hospital National Health Service Foundation Trust and University College London Institute of Ophthalmology for a Biomedical Research Centre for Ophthalmology. The sponsors or funding organizations had no role in the design or conduct of this research.
HUMAN SUBJECTS: Human subjects were not included in this study. All research adhered to the tenets of the Declaration of Helsinki. This study involved only review and synthesis of existing literature, and was exempt from Institutional Review Board approval. The requirement for informed consent was waived because of the retrospective nature of the study.
No animal subjects were used in this study.
Author Contributions:
Conception and design: Stuart, Madjedi, Foster, Khawaja
Data collection: Stuart, Madjedi, Foster, Khawaja
Analysis and interpretation: Stuart, Madjedi, Luben, Chua, Warwick, Chia, Pasquale, Wiggs, Kang, Hysi, Tran, Foster, Khawaja
Obtained funding: Foster
Overall responsibility: Stuart, Madjedi, Luben, Chua, Warwick, Chia, Pasquale, Wiggs, Kang, Hysi, Tran, Foster, Khawaja
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P.J.F. and A.P.K. are joint senior authors.
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Members of the Modifiable Risk Factors for Glaucoma Collaboration are available at www.aaojournal.org