Original articleThe Incidence of Central Serous Chorioretinopathy in Olmsted County, Minnesota, 1980–2002
Section snippets
Materials and Methods
Institutional review board approval was obtained for this retrospective chart review study. The Rochester Epidemiology Project is a medical linkages system designed to capture data on any patient–physician encounter in Olmsted County, Minnesota, a semiurban community.14 Population-based epidemiologic research is possible in Olmsted County because medical care is essentially self-contained within the community, provided by either the Mayo Clinic or the Olmsted Medical Group and its affiliated
Results
An initial search revealed 107 cases of CSC in Olmsted County, Minnesota from 1980 to 2002. On further review, 35 cases were excluded for the following reasons: no fluorescein angiogram obtained (23 cases), no CSC on review of the fluorescein angiogram (10), and not in Olmsted County at the time of diagnosis (2). We reviewed all the coded cases of pigment epithelial detachment in patients younger than 60 from 1980 through 2002. There were 2 cases of CSC misdiagnosed as pigment epithelial
Discussion
Our study provides the only known population-based data on the incidence of CSC. We found the overall incidence to be 5.8 per 100 000 people. The age-adjusted incidence in males was significantly higher, at 9.9 per 100 000, about 5 to 6 times higher than the incidence in females. The male-to-female ratio of 5.7:1 in this study is higher than the reported ratios of 2.2:1 to 4.2:1 in other case–control studies.2, 4, 5, 6, 7, 19 In the non–case–control literature regarding CSC, a higher male to
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Manuscript no. 2006-1399.
Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, New York.
The authors have no proprietary interest in any aspect of the article.