Original ArticlePulsatile Blood Flow in the Polypoidal Choroidal Vasculopathy
Section snippets
Patients and Methods
A retrospective review identified 84 eyes of 74 patients diagnosed with PCV during the period between July, 1998, and April, 2004, at Kagoshima University Hospital. All patients underwent comprehensive ophthalmologic examination, including best-corrected visual acuity, intraocular pressure, biomicroscopy, dilated funduscopic examination, fluorescein angiography, and ICGA (Topcon, Tokyo, Japan). The clinical diagnosis of PCV was based on the presence of PVs on ICGA corresponding to clinically
Results
A total of 84 eyes of 74 Japanese patients met the study criteria. Patients ranged in age from 47 to 91 years (mean±standard deviation, 68.0±8.7 years). Sixty-four (86.5%) had unilateral eye involvement and 10 had bilateral involvement. Men were predominantly affected (71.6%). Mean follow-up time after diagnosis of PCV was 23.3 months (range, 1–71 months). Thirty-three patients (44.6%) were being treated for systemic hypertension, hypercholesterolemia, or both.
Discussion
We examined 74 Japanese cases with PCV retrospectively and found pulsatile PVs in 7 patients (9.5%). No reports in the English literature are available on pulsatile PV, although there are a few brief descriptions in the Japanese literature.20, 21, 22 Notably, the period of pulsatile PVs detectable on ICGA is limited in each case. In patient 5, the pulsatile movement of PV disappeared within 5 weeks. In patient 6, the pulsatile movement of 2 PVs was observed for at least 6 to 15 months and
Acknowledgments
The authors thank Dr Teruto Hashiguchi of the Department of Laboratory and Vascular Medicine and Dr Masaaki Miyata of the Department of Cardiovascular, Respiratory and Metabolic Medicine in Kagoshima University Graduate School of Medical and Dental Sciences for helpful discussion to interpret the pulsatile blood flow.
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Observation of a pulsatile choroidal vascular lesion in a patient with polypoidal choroid vasculopathy during vitrectomy
2022, American Journal of Ophthalmology Case ReportsCitation Excerpt :This circulation was originally described as a branching vascular network that formed polypoidal lesions. Pulsatile choroidal polyps were observed in previous studies that used fundus angiography to assess the choroidal hemodynamics, and provided important clues to understand the pathogenesis of PCV.1–3 Here we report an interesting finding: a pulsating choroidal vascular lesion that was visible during vitrectomy in a patient undergoing treatment of vitreous hemorrhage secondary to PCV.
Numerous retinal pigment epithelial elevations and drusen associated with unusual dilated choroidal vessels seen at choriocapillaris level in macular area
2020, American Journal of Ophthalmology Case ReportsCitation Excerpt :This was because the veins converged and exited the posterior pole. The direction of the blood flow was different from those in the branched vascular networks, which consisted of not only a venous component but also an arterial component.6,7 Normally, the choroidal venous drainage occurs through the vortex veins in the equatorial region of the eye.8
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2019, Journal Francais d'OphtalmologieSensitivity and specificity of spectral-domain optical coherence tomography in detecting idiopathic polypoidal choroidal vasculopathy
2014, American Journal of OphthalmologyCitation Excerpt :In the early phase of the ICGA, a pulsation of a polypoidal vessel may occasionally be seen.12 However, with the advent of new imaging techniques, such as SD OCT, the diagnostic accuracy of this condition has improved and new histopathologic characteristics have been described by different authors.5–13 Some reports have also shown an association of PCV with other diseases such as sickle cell,14 central retinal vein occlusion,15 retinitis pigmentosa,16 CSCR,17 and melanocytoma.18
Polypoidal Choroidal Vasculopathy: A Review
2010, Survey of OphthalmologyCitation Excerpt :The higher transmittance of light above 800 nm and the strong intravascular retention of the ICG molecule allow better resolution of the choroidal vasculatures. In the early phase of ICGA, pulsation of polypoidal vessels may sometimes be observed.63 Seven of 74 patients (9.5%) with PCV had pulsatile polypoidal vessels in the macula.63
Imaging-based Assessment of Choriocapillaris: A Comprehensive Review
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Manuscript no. 2005-21.
Supported by the Japanese Ministry of Education, Science, Sports and Culture, Tokyo, Japan (research grant no.: 17591844).
The authors have no propriety interests.