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NeuroImage
Volume 33, Issue 2, 1 November 2006, Pages 784-793
 
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doi:10.1016/j.neuroimage.2006.06.057    How to Cite or Link Using DOI (Opens New Window)
Copyright © 2006 Elsevier Inc. All rights reserved.

How metaphors influence semantic relatedness judgments: The role of the right frontal cortex

Argyris K. Stringarisa, Corresponding Author Contact Information, 1, E-mail The Corresponding Author, Nicholas Medforda, 1, Rachel Giorac, Vincent C. Giampietrob, Michael J. Brammerb and Anthony S. Davida

aSection of Cognitive Neuropsychiatry, Institute of Psychiatry at the Maudsley, King’s College London, PO 68 Denmark Hill, London SE5 8AF, UK bBrain Image Analysis Unit, Institute of Psychiatry at the Maudsley, King’s College London, UK cDepartment of Linguistics, Tel Aviv University, Israel

Received 4 February 2006; 
revised 22 June 2006; 
accepted 29 June 2006. 
Available online 11 September 2006.

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Abstract

We used event-related fMRI (ER-fMRI) to test the hypothesis that metaphors bias cognitive processing of semantic relatedness towards a search for a wider range of associations. Twelve right-handed male volunteers read a mixture of metaphoric and literal sentences, each sentence being followed by a single word, which could be semantically related or not to the preceding sentence context. We found that judging unrelated words as contextually irrelevant was associated with increased blood oxygenation level-dependent (BOLD) signal in the right ventrolateral prefrontal cortex in the metaphoric but not in the literal condition. The same region was also activated when subjects endorsed a semantic relation between words and metaphoric sentence primes but not between words and literal sentence primes. We argue that these results are consistent with the notion of semantic open-endedness, whereby figurative statements bias cognitive processing towards a search for a wider range of semantic relationships compared to literal statements, and thus lend further support to the view that coarse semantic coding occurs preferentially in the right hemisphere.

Article Outline

Introduction
Methods
Participants
Experimental stimuli and design of the task
Experimental procedure
Analysis of behavioral data
Image acquisition
Individual brain activation maps
Group maps
Sensitivity of detection of fMRI responses
Results
Behavioral results and discussion
fMRI results and discussion
Rejecting irrelevant meanings
Endorsing relevant meanings
General discussion
Acknowledgements
References


NeuroImage
Volume 33, Issue 2, 1 November 2006, Pages 784-793
 
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