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doi:10.1016/j.neucli.2005.03.002 
Copyright © 2005 Elsevier SAS All rights reserved.
Original article
Late event-related potentials and movement complexity in young adults with Down syndrome
Received 13 December 2004;
| Referred to by: | | Erratum to “Late event-related potentials and movement complexity in young adults with Down syndrome” [Neurophysiol. Clin. 35 (2005) 81–91] Neurophysiologie Clinique/Clinical Neurophysiology, Volume 35, Issue 4, October 2005, Pages 147-148 Elodie Lalo, Laurent Vercueil, Thierry Bougerol, Pierre-Simon Jouk, Bettina Debû  PDF (256 K)
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Abstract
Objectives. – Through event-related potential (ERP) recording, to better understand the perceptive-motor slowness in adults with Down syndrome (DS); in particular, to assess whether motor preparation influences the speed of allocation of perceptual attention as reflected by the P3 latency.
Patients and methods. – ERPs were obtained in adults with and without DS through an auditory oddball paradigm under a passive and two active (simple vs. complex motor response) conditions. Reaction times (RTs) were recorded in the two active conditions.
Results. – There was no influence of movement complexity on either RT or P3b latency in the control group. In the DS group, RT was delayed under simple vs. complex conditions whereas P3b latency was not affected. N2a and N2b were often missing in DS individuals.
Conclusion. – Motor preparation processes per se rather than interaction with perceptual attention could be defective in individuals with DS when the motor component of the response is minimal.
Résumé
Buts. – Au moyen des potentiels liés à l'événement (PLE), comprendre la lenteur perceptivomotrice des individus porteurs de trisomie 21 (T21) et vérifier si, dans ce groupe, les processus de préparation motrice influencent la vitesse d'allocation de l'attention perceptive reflétée par le temps de latence de la P3.
Patients et méthodes. – les PLE ont été enregistrés chez des adultes T21 et témoins au moyen d'un paradigme du stimulus discordant auditif dans une condition passive et deux conditions actives (réponse motrice simple ou complexe). Les temps de réaction (TR) ont été mesurés dans les conditions actives.
Résultats. – Chez les témoins, ni le TR ni le temps de latence de la P3b n'étaient influencés par la complexité du mouvement. Dans le groupe T21, le TR était plus long en condition simple qu'en condition complexe tandis que le temps de latence de la P3b était insensible à la complexité du mouvement; les composantes N2a et N2b étaient souvent absentes.
Conclusions. – les processus d'attention motrice en tant que tels plutôt que leurs interactions avec les processus d'attention perceptive sont altérés chez les individus T21 lorsque la composante motrice de la réponse est minimale.
Keywords: Down syndrome; Perceptual and motor attention; ERPs; P300; Motor complexity
Mots clés: Trisomie 21; Attention perceptive et motrice; PLE; Complexité motrice
Article Outline
- 1. Introduction
- 2. Materials and methods
- 2.1. Participants
- 2.2. Stimulation procedure
- 2.3. Experimental procedure
- 2.4. Electromyography (EMG) recording
- 2.5. ERP recording
- 2.6. Data analysis
- 2.7. Descriptive analysis
- 2.7.1. Exogenous components
- 2.7.2. Endogenous components
- 2.8. Quantitative analysis
- 3. Results
- 4. Discussion
- 4.1. Specificity of slow and late ERP responses in individuals with DS
- 4.1.1. Passive condition
- 4.1.2. Active conditions
- 4.2. Impact of the motor demand of the task on information processing under active conditions
- Acknowledgements
- References
