Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis
Under a Creative Commons license
open access
Keywords
Ovarian cancer
Peritoneum
Metastasis
Thrombospondin-1
Vitamin D
Epithelial-mesenchymal transition (EMT)
Abbreviations
OvCa
ovarian cancer
MC
mesothelial cell
CAM
cancer-associated mesothelial cell
CAF
cancer-associated fibroblasts
TGF-β1
transforming growth factor beta 1
TGFβ-RI
TGF-β1 receptor inhibitor
EMT
epithelial-mesenchymal transition
MET
mesenchymal-epithelial transition
ECM
extracellular matrix
VD
vitamin D
VDR
vitamin D receptor
THBS1
thrombospondin-1
FACS
fluorescence-activated cell sorting
GSEA
Gene Set Enrichment Analysis
TCGA
The Cancer Genome Atlas
DAVID
Database for Annotation, Visualization and Integrated Discovery
FBS
fetal bovine serum
Cited by (0)
© 2022 The Author(s). Published by Elsevier B.V.