Short communicationSub-viral imaging of vaccinia virus using super-resolution microscopy
Highlights
► Imaging of single vaccinia virus particles at sub-viral resolution was achieved using 3D-SIM. ► The viral envelope protein B5 was resolved as a spherical structure encompassing the virus cores. ► Maturation and morphogenesis of virus particles is now accessible to light microscopy analysis.
Section snippets
Acknowledgements
This work was supported by the Australian Research Council Federation Discovery Project (DP1096623). CBW is supported by an Australian National Health and Medical Research Council Senior Research Fellowship. We would like to thank the members of the Newsome Lab for their helpful comments.
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