Journal of Minimally Invasive Gynecology
Oral PresentationApplication of Narrow-Band Imaging Hysteroscopy in the Diagnosis of Endometrial Lesions
Section snippets
Study Objective
To investigate the value of narrow-band imaging (NBI) technology for improving the diagnostic reliability of hysteroscopy by studying the application of NBI and white light imaging (WLI) hysteroscopy in the diagnosis of endometrial lesions.
Design
Clinical Study.
Setting
Minimally Invasive Center of Beijing Obstetrics and Gynecology Hospital.
Patients
From March 2011 to November 2013, a total of 213 patients with suspected endometrial lesions.
Intervention
The patients with suspected endometrial lesions were examined with hysteroscopy equipped with the white light mode and NBI mode.Using the pathological diagnosis as the gold-standard, we evaluated the value of NBI hysteroscopy for detecting positive lesions which included endometrial carcinoma and atypical endometrial hyperplasia .
Measurements and Main Results
A total of 442 lesions in 213 patients were detected by WLI and NBI hysteroscopy.Simple hyperplasia and complicacy hyperplasia): The sensitivity of NBI and WLI was 79.6%(39/49) and 49.0%(24/49), P=0.003; the specificity of NBI and WLI was 99.0%(389/393) and 97.2%(382/393), P=0.039. Atypical endometrial hyperplasia: The sensitivity of NBI and WLI was 93.5%(86/92) and 82.6%(76/92), P=0.006; the specificity of NBI and WLI was 99.1%(347/350) and 92.3%(332/350), P=0.001. Endometrial carcinoma: The
Conclusion
NBI hysteroscopy can improve the sensitivity and specificity of the diagnosis of endometrial lesions. Hysteroscopic diagnosis has better concordance with pathological diagnosis in the NBI mode. NBI hysteroscopy was easy to be applied in uterine cavity examination and endometrial biopsy with high sensitivity and specificity by detection of the morphology of mucosal capillary vessels. It not only improved the relevance and accuracy of the biopsy, but also reduced the missed diagnosis of