Original ResearchDynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids
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Author contributions Ophélie Nicolle and Sophia Maschalidi contributed equally to this work; Mohammed H. Mosa, Ophélie Nicolle, Sophia Maschalidi, Aurelien Bidaud-Meynard, and Henner F. Farin performed the experiments; Fernando E. Sepulveda, Constantin Menche, and Birgitta E. Michels provided technical support; Mohammed H. Mosa, Ophélie Nicolle, Aurelien Bidaud-Meynard, Grégoire Michaux, and Henner F. Farin analyzed the data; Grégoire Michaux, Geneviève de Saint Basile, and Henner F. Farin conceived the study, supervised the experiments, and obtained funding; and Geneviève de Saint Basile and Henner F. Farin drafted the manuscript. All authors discussed the results and commented on the manuscript.
Conflicts of interest The authors disclose no conflicts.
Funding Supported by the French National Institute of Health and Medical Research (INSERM), the Agence Nationale de la Recherche Hemophagocytic lymphohistiocytosis-Cytotox/ANR-12-BSV1-0020-01 (G.d.S.B.), the LOEWE Center for Cell and Gene Therapy Frankfurt, Hessisches Ministerium für Wissenschaft und Kunst (H.F.F.), and by the Centre national de la recherche scientifique and the Ligue Régionale Contre le Cancer (22/29/35/72) (G.M.).
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Authors share co-senior authorship.