Regular Research ArticleA Randomized Cross-over Controlled Study on Cognitive Rehabilitation of Instrumental Activities of Daily Living in Alzheimer Disease
Section snippets
Participants
Twenty patients were recruited from May 2008 to March 2011 at the Alzheimer Society (Quebec City Division) (N = 6), at homes for the elderly (N = 5), using public advertisement and local papers (N = 5), at Memory Disorders Clinic (N = 3), and through an ongoing research project (N = 1). The participants had to meet the following inclusion criteria: 1) diagnosis of AD,10 confirmed by medical records, history, and results of the neuropsychological evaluation performed at screening; 2) be in mild
Participant's Characteristics
Ten patients per group participated in the trial. One participant (Group 1) abandoned the trial during the intervention phase because of his high level of anxiety, and two participants in Group 2 withdrew after baseline evaluation because of 1) the caregiver's high level of burden (first patient) and 2) dissatisfaction of the participant regarding the randomization process (second patient). Because insufficient data was available for these participants, they were excluded from the analyses.
Discussion
This trial demonstrated the effectiveness of cognitive rehabilitation to re-learn IADLs in patients with mild to moderate AD—all patients significantly improved their performances following training compared to baseline. Moreover, a significant difference between Group 1 (trained) and Group 2 (untrained) was found at post-treatment 1, which underlines the positive effect of the cognitive intervention. The improvements of both groups were maintained, to some extent, 2 to 3 months after the end
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2019, Ageing Research ReviewsCitation Excerpt :Recommended management methods highly supported by National Institute for Health and Care Excellence(NICE) for dementia-related symptoms involving NPTs have become increasingly accepted for controlling the progression of dementia or retarding the cognitive impairment to dementia, most notably AD. The most common NPTs, such as Cognitive stimulation therapy(CST), Cognitive rehabilitation(CR), Music therapy(MT), Reminiscence therapy(RT), as well as Computerized cognitive training(CCT), a special treatment focusing primarily on reducing underlying cognitive impairment or slowing its progression in AD patients (Hill et al., 2017), which has already been manifested by previous studies, and the NPTs mentioned above were generally demonstrated by previous studies on their efficacy not only in improving the cognition in AD patients but also executive functioning, behavior, and global quality of daily life (Luchsinger et al., 2005; Orrell et al., 2014; Thivierge et al., 2014). Also worth noting is that the more popular sensory interventions, namely, multisensory stimulation environment(MSSE), was aimed at helping people with severe or very severe dementia under a Snoezelen multisensory environment by stimulating the primary senses without the need for intellectual activity (Maseda et al., 2014; Sánchez et al., 2016a, b).
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