Editorial
2nd International Conference on Human Biomonitoring, Berlin 2016

https://doi.org/10.1016/j.ijheh.2017.01.004Get rights and content

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  • Implementation and coordination of an ethics framework in HBM4EU – Experiences and reflections

    2023, International Journal of Hygiene and Environmental Health
    Citation Excerpt :

    Biobanked samples and previously published data from some of the 17 countries participating in the previous European DEMOCOPHES project were re-used. The DEMOCOPHES samples were originally collected in 2011–2012 using common protocols including an obligation to store samples for 10 years from 2011 on (Fiddicke et al., 2015; Schwedler et al., 2017; Casteleyn et al., 2015). New analysis of the biobanked samples required renewed ethical approval in some countries.

  • Metabolism and urinary excretion kinetics of di(2-ethylhexyl) adipate (DEHA) in four human volunteers after a single oral dose

    2020, Toxicology Letters
    Citation Excerpt :

    Given its use in consumer products, food contact materials, and medical devices (Scientific Committee on Emerging and Newly-Identified Health Risks (SCENIHR), 2016), and considering its presence in the aquatic environment (Horn et al., 2004; Barnabé et al., 2008) and in indoor environments (e.g. indoor air and dust) (Fromme et al., 2016; Subedi et al., 2017; Christia et al., 2019; Giovanoulis et al., 2019), exposures of the general population to DEHA are highly likely. Human biomonitoring (HBM) is a well-established tool for conducting integral (covering all exposure sources and uptake routes) exposure assessments, both on an individual and population level (Needham et al., 2007; Schindler et al., 2014; Haines et al., 2017; Kolossa-Gehring et al., 2017; Schwedler et al., 2017). For several phthalate-type plasticizers and non-phthalate plasticizer substitutes, exposure biomarkers are established and have been applied for exposure assessments in large-scale population studies (Zota et al., 2014; Koch et al., 2017; Silva et al., 2017; Kasper-Sonnenberg et al., 2019; Lessmann et al., 2019).

  • Urinary metabolites of the UV filter 2-Ethylhexyl salicylate as biomarkers of exposure in humans

    2019, Toxicology Letters
    Citation Excerpt :

    Given the widespread use of EHS in PCPs resulting in direct EHS contact of consumers, and further considering its presence in the environment, the determination of EHS body burdens is of high interest. Human biomonitoring (HBM) provides an integral measure of exposure to chemicals, covering all exposure sources and uptake routes, and is well established for exposure assessment both in large scale population studies and on an individual level (Angerer et al., 2007; Needham et al., 2007; Schindler et al., 2014; Haines et al., 2017; Kolossa-Gehring et al., 2017; Schwedler et al., 2017). Recently, we described an HBM method for the determination of three specific urinary metabolites of EHS (Bury et al., 2019a), which were identified in the current metabolism study: 2-ethyl-5-hydroxyhexyl 2-hydroxybenzoate (5OH-EHS), 2-ethyl-5-oxohexyl 2-hydroxybenzoate (5oxo-EHS), and 5-(((2-hydroxybenzoyl)oxy)methyl)heptanoic acid (5cx-EPS).

  • Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS/MS

    2019, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
    Citation Excerpt :

    Accordingly, the determination of internal EHS exposure of humans is of high interest. Human biomonitoring (HBM) is a well-established tool for exposure assessment, covering all exposure sources and uptake routes and applicable both to large scale population studies and individual exposure assessment [29–35]. However, exposure biomarkers for EHS and analytical methods for their determination have not been published yet.

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The findings and conclusions in this report are those of the author and do not necessarily represent the official position of the US Centers for Disease Control and Prevention.

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