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doi:10.1016/j.eswa.2005.09.076    
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Copyright © 2005 Elsevier Ltd All rights reserved.

A knowledge-based approach to assign breast cancer treatments in oncology units

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Teddy G. Miranda-Menaa, 1, E-mail The Corresponding Author, Sandra L. Benítez U.a, 1, E-mail The Corresponding Author, José Luis Ochoaa, 1, E-mail The Corresponding Author, Rodrigo Martínez-Béjara, 1, E-mail The Corresponding Author, Jesualdo Tomás Fernández-Breisb, Corresponding Author Contact Information, E-mail The Corresponding Author and Juan Salinasc, 2

aDepartamento de Ingeniería de la Información y las Comunicaciones, Universidad de Murcia, 30071-Espinardo (Murcia), España

bDepartamento de Informática y Sistemas, Universidad de Murcia, 30071-Espinardo (Murcia), España

cServicio de Oncología y Radioterapia. Hospital Virgen de la Arrixaca, 30120-El Palmar (Murcia), España


Available online 17 October 2005.

Abstract

The aim of this work is to present a developed knowledge-based approach for breast cancer treatment. This Decision Support System (DSS) uses an incremental knowledge acquisition technique called Multiple Classification Ripple Down Rules (MCRDR) and a breast cancer treatments knowledge base. This system integrate MCRDR inference engine and use knowledge bases to reach advanced reasoning level during the decision making process. The knowledge base will be built from clinical protocols, and its content will be updated by the doctor using the MCRDR component. This DSS infers a cancer treatment from the (clinical or pathological) input data supplied by the physician and it also allows the maintenance of the knowledge base.

Keywords: Knowledge acquisition; Knowledge representation; Decision support system; Breast cancer; Protocols and guidelines; Validation and verification

Article Outline

1. Introduction
2. Modelling the concepts of the knowledge-based system
3. Construction of the breast cancer treatments knowledge base
4. The Oncology Decision Support Tool
4.1. Patients.
4.2. Inference engine
4.3. Knowledge acquisition and maintenance
4.4. Explaining conclusions
5. Validation
6. Conclusions
Acknowledgements
References






Corresponding Author Contact InformationCorresponding author. Tel.: +34 968364613; fax: +34 968364151.
1 Tel.: +34 968364634; fax: +34 968364151. http://klt.dif.um.es
2 Tel.: +34 968369502.

 
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