The companion paper presents the principles of a new design-oriented methodology for progressive collapse assessment of multi-storey buildings. The proposed procedure, which can be implemented at various levels of structural idealisation, determines ductility demand and supply in assessing the potential for progressive collapse initiated by instantaneous loss of a vertical support member. This paper demonstrates the applicability of the proposed approach by means of a case study, which considers sudden removal of a ground floor column in a typical steel-framed composite building. In line with current progressive collapse guidelines for buildings with a relatively simple and repetitive layout, the two principal scenarios investigated include removal of a peripheral column and a corner column. The study shows that such structures can be prone to progressive collapse, especially due to failure of the internal secondary beam support joints to safely transfer the gravity loads to the surrounding undamaged members if a flexible fin-plate joint detail is employed. The provision of additional reinforcement in the slab over the hogging moment regions can generally have a beneficial effect on both the dynamic load carrying and deformation capacities. The response can be further improved if axial restraint provided by the adjacent structure can be relied upon. The study also highlights the inability of bare-steel beams to survive column removal despite satisfaction of the code prescribed structural integrity provisions. This demonstrates that tying force requirements alone cannot always guarantee structural robustness without explicit consideration of ductility demand/supply in the support joints of the affected members, as determined by their nonlinear dynamic response.