Short report
Primary Intravascular Synovial Sarcoma of the Femoral Vein in a Male Patient, Case Report

https://doi.org/10.1016/j.ejvs.2008.01.028Get rights and content
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Abstract

Synovial Sarcoma (SS) is an aggressive neoplasm commonly affecting deep soft tissues of the extremities. In rare instances SS can arise in large veins of the lower extremities or trunk. We report the first case of intravascular synovial sarcoma (IVSS) occurring in a male patient. A biphasic tumor was diagnosed by histology and immunohistochemistry. Molecular analysis at RNA level confirmed the diagnosis demonstrating the chromosomal translocation t(X;18) (p11.2;q11.2) in the tumor. Although extremely rare, IVSS should be considered in the differential diagnosis of primary intravascular neoplasms and as a potential cause of deep vein thrombosis and thromboembolism.

Keywords

Sarcoma, Synovial
Venous thrombosis
Venous thromboembolism
Vascular neoplasms

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