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Discrete Applied Mathematics
Volume 154, Issue 12, 15 July 2006, Pages 1753-1758
 
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doi:10.1016/j.dam.2006.02.006    
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Copyright © 2006 Elsevier B.V. All rights reserved.

On error-tolerant DNA screeningstar, open

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Weili Wua, Corresponding Author Contact Information, E-mail The Corresponding Author, Yaochun Huanga, Xiao Huangb, E-mail The Corresponding Author and Yingshu Lic, E-mail The Corresponding Author

aDepartment of Computer Science, University of Texas at Dallas, Richardson, TX 75083, USA

b3M Center, Building 0235-03-F-08, St. Paul, MN 55144, USA

cDepartment of Computer Science, Georgia State University, Atlanta, GA 30303, USA


Received 4 December 2003; 
revised 25 January 2006; 
accepted 3 February 2006. 
Available online 25 April 2006.

Abstract

Given n clones with some positive ones, the problem of DNA screening is to identify all positive clones with a set of tests each on a subset of clones, called a pool and the outcome is either the pool contains a positive clone or not. In this paper, we show that for a class of designs, if we apply those for samples with d positive clones to samples with at most d-1 positive clones, the error-tolerant property will have an interesting improvement. We also make a remark on decoding method for k-error-correcting d-disjunct matrix.

Keywords: DNA screening; Error tolerant; Pooling design; Group testing

Article Outline

1. Introduction
2. Construction with simplicial complex
3. Remark on decoding
4. Discussion
References

star, openSupport in part by National Science Foundation under grant ACI-0305567.


Corresponding Author Contact InformationCorresponding author.

Discrete Applied Mathematics
Volume 154, Issue 12, 15 July 2006, Pages 1753-1758
 
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