Cell Metabolism
Volume 13, Issue 2, 2 February 2011, Pages 119-120
Journal home page for Cell Metabolism

Preview
AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy

https://doi.org/10.1016/j.cmet.2011.01.009Get rights and content
Under an Elsevier user license
open archive

AMP-activated protein kinase (AMPK) is a highly conserved cellular energy sensor that plays a central role in metabolic homeostasis. A recent study in Science (Egan et al., 2011) identifies ULK1 as a substrate for AMPK phosphorylation, a modification required for selective autophagy of mitochondria and cell survival during starvation.

Cited by (0)