Cell Reports
Volume 34, Issue 1, 5 January 2021, 108532
ArticleFunctional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
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open access
Graphical Abstract
Keywords
heterobifunctional proteolysis-targeting chimeric compounds
pharmacological degraders
resistance
CRISPR
CRBN
VHL
myeloma
PROTAC
E3 ligase
CRISPR activation
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