Zn(NO3)2·6H2O/2,4,6-trichloro-1,3,5-triazine (TCT) a mild and selective system for nitration of phenols

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Abstract

Certain phenols and naphthols were nitrated regioselectively with Zn(NO3)2·6H2O/TCT in acetonitrile as solvent at room temperature and short reaction time in good yields. The reaction condition was mild. TCT is a cheap and commercially available reagent. It performed as an acid catalyst in this transformation.

Section snippets

Experimental

Chemicals were purchased from the Fluka, Merck and Aldrich chemical companies. The nitration products characterized by comparison of their spectral (IR, 1H NMR), TLC and melting point with authentic samples.

Acknowledgment

We thank the Department of Chemistry of Semnan University for supporting this work.

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Copyright © 2009 Firouzeh Nemati. Published by Elsevier B.V. All rights reserved.