Letter to the EditorMonotherapy with tDCS for Schizophrenia: A Case Report
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Cited by (35)
Brain connectivity and auditory hallucinations: In search of novel noninvasive brain stimulation therapeutic approaches for schizophrenia
2016, Revue NeurologiqueCitation Excerpt :The number of sessions varied from five [118,123] to 20 [115]. AVH were assessed with the AHRS [110–114,117,119,120,123], the PANSS [115,123,125], the PSYRATS [114,118] and the HCS [109]. All of the case studies cited above, excepting one [113], reported improvements of AVH.
A systematic review of the clinical efficacy of transcranial direct current stimulation (tDCS) in psychiatric disorders
2016, Journal of Psychiatric ResearchCitation Excerpt :A number of case reports/series describing patients with refractory schizophrenia have also offered support (Brunelin et al., 2012b; Jacks et al., 2014; Narayanaswamy et al., 2014; Nawani et al., 2014a, 2014b; Rakesh et al., 2013; Shenoy et al., 2015; Shivakumar et al., 2014). For instance, Shenoy et al. (2015) recorded near-total improvement of the exacerbation of AVHs during pregnancy, Narayanaswamy et al. (2014) noted a delayed but persistent improvement in negative symptoms, and Rakesh et al. (2013) observed complete cessation of AVHs immediately after the first two tDCS sessions and at post-intervention re-assessment. Shivakumar et al. (2014) also witnessed a tDCS-induced termination of AVHs, and subsequently found that application of intermittent booster tDCS (6 sessions) resulted in sustained improvements for a period of one year.
Impact of antipsychotic medication on transcranial direct current stimulation (tDCS) effects in schizophrenia patients
2015, Psychiatry ResearchCitation Excerpt :tDCS has been demonstrated to be effective in reducing auditory hallucinations by presumably decreasing hyperactivity of the temporo-parietal junction (TPJ) in the first monocentric proof-of-principle trial (Brunelin et al., 2012). Indeed, pilot studies have demonstrated a significant clinical improvement with tDCS, with respect to auditory hallucinations (Brunelin et al., 2012; Mondino et al., 2015b; Rakesh et al., 2013; Shivakumar et al., 2013), negative symptoms (Brunelin et al., 2012; Kurimori et al., 2015; Mondino et al., 2015b) and insight into the origin and reality of psychotic experiences (Bose et al., 2014). Several factors are known or presumed to affect the neuroplasticity-inducing potential of tDCS, such as subjects’ age and sex, genetic profile, history of past response to tDCS or repetitive transcranial magnetic stimulation (rTMS) and medication (Ridding and Ziemann, 2010).
Clinical use of Transcranial Direct Current Stimulation in Psychiatry
2014, The Stimulated Brain: Cognitive Enhancement Using Non-Invasive Brain StimulationModulation of Corollary Discharge Dysfunction in Schizophrenia by tDCS: Preliminary Evidence
2014, Brain Stimulation
Financial support: GR, AS, HN and JCN are supported by the Department of Science & Technology, Government of India. VS is supported by the Indian Council of Medical Research. ACA & GV are supported by the Wellcome Trust/DBT India Alliance.
Conflict of interest: There are no potential conflicts of interest to report for any of the authors.