Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane
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Abbreviations
ATR-FTIR
attenuated total reflection Fourier transform infrared
CD
circular dichroism
DMPA
dimyristoyl phosphatidic acid
DMPC
dimyristoyl phosphatidylcholine
DMPG
dimyristoyl phosphatidyglycerol
DMPS
dimyristoyl phosphatidylserine
DSC
differential scanning calorimetry
LUV
large unilamellar vesicle
MLV
multilamellar vesicle
NMR
nuclear magnetic resonance
P/L
peptide/lipid ratio
PI(4,5)P2
l-α-phosphatidylinositol-4,5-bisphosphate
POPA
palmitoyl-oleoyl-phosphatidic acid
POPC
palmitoyl-oleoyl-phosphatidylcholine
POPE
palmitoyl-oleoyl-phosphatidylethanolamine
POPG
palmitoyl-oleoyl-phosphatidylglycerol
POPS
palmitoyl-oleoyl-phosphatidylserine
DPC
1,2-di-0-dodecyl-sn-glycero-3-phosphocholine
SDS
sodium dodecyl sulfate
PWR
plasmon waveguide resonance
SUVs
small unilamellar vesicles
Keywords
TRP channels
Peptide–lipid interactions
Secondary structure
Conformation
Lipid-selective interaction
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