Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1843, Issue 11, November 2014, Pages 2645-2661
Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite
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Graphical abstract
Abbreviations
AG
aminoguanidine
BrdU
bromodeoxyuridine
DAF2DA
4, 5-diaminofluorescein diacetate
DCFDA
2′, 7′-dichlorofluorescin diacetate
DHR123
dihydrorhodamine 123
FeTPPS
5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrinato iron (III), chloride
FITC
fluorescein isothiocyanate
Ifnγ
interferon-gamma
IfnγR
interferon-gamma receptor
Irf1
interferon regulated factor 1
JC-1
5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide
Jnk
cJun-N-terminal kinase
Lmp10
proteasome (prosome, macropain) subunit beta type 10
LNMA
NG-methyl-l-arginine
LPS
lipopolysaccharide
MHC-I
Major Histocompatibility Complex encoded Class I
NO
nitric oxide
Nos2
nitric oxide synthase 2
3-NT
3-nitro tyrosine
PEG–CAT
polyethyleneglycol–catalase
PEG–SOD
polyethyleneglycol–superoxide dismutase
ROS
reactive oxygen species
RNI
reactive nitrogen intermediates
SNAP
S-Nitroso-N-acetyl-DL-penicillamine
Stat1
signal transducer and activator of transcription 1
t-BHP
tert-butyl hydroperoxide
ΔΨm
loss of mitochondrial membrane potential
Keywords
Interferon-gamma
Cell death
Oxidative stress
Nitrosative stress
Mitogen activated protein kinase
Free radical
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