Coronary Artery DiseaseComparison of Different Risk Scores for Predicting Contrast Induced Nephropathy and Outcomes After Primary Percutaneous Coronary Intervention in Patients With ST Elevation Myocardial Infarction
Section snippets
Methods
This study prospectively enrolled a series of consecutive patients with STEMI who underwent PPCI at Guangdong General Hospital, from March 2010 to October 2012. Acute STEMI was defined as the presence of typical chest pain and accompanying symptoms for ≥30 minutes but <12 hours in the presence of ST-segment elevation ≥1 mm in at least 2 continuous leads or a new or undetermined duration of left branch bundle block with ≥2 times increase in cardiac enzymes (troponin I or T).10 Patients were
Results
A total of 422 consecutive patients (age: 62.48 ± 12.45 years) with STEMI were included in the present study. Baseline characteristics, medications, procedural variables, and the mean of all risk scores are presented in Table 2. Of the entire cohort, 15.2% patients were women, 49.3% had hypertension, 22% had diabetes mellitus, and 35.1% had anemia. Complete follow-up was achieved in 91.6% of patients (35 patients were lost to follow-up). The overall incidence of CIN was 7.3% for CIN-narrow and
Discussions
The present study demonstrated that the risk scores tested had high discriminatory ability with the majority also having good calibration for CIN-narrow, in-hospital death and MACEs, and 3-year all-cause mortality, in patients with STEMI receiving PPCI. The ACEF and AGEF risk scores had slightly better prognostic values than other risk scores. However, when predicting CIN-broad and 3-year MACEs, all scores showed poor discriminatory ability.
Identification and intervention for patients with
Disclosures
The authors have no conflicts of interest to disclose.
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2018, International Journal of CardiologyCitation Excerpt :Most importantly, the ACEF score had a similar accuracy in our patient cohort as when applied to patients undergoing elective cardiac surgery, for which the score was initially developed [9]. These findings are supported by a previous single-centre study enrolling patients with STEMI suggesting a high predictive accuracy of the ACEF score in this patient subset and a previous retrospective analysis of the randomized Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial including moderate- to high-risk NSTEMI patients in the early generation drug-eluting stent era [28, 29]. The predictive value of the ACEF score seems, however, to be limited in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement [30].
Renal protective effects of sodium bicarbonate tablets after coronary artery angiography
2023, Chinese Journal of Clinical ResearchContrast-induced acute kidney injury and its contemporary prevention
2022, Frontiers in Cardiovascular Medicine
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