Preventive cardiologyComparison of the Prognostic Significance of the Electrocardiographic QRS/T Angles in Predicting Incident Coronary Heart Disease and Total Mortality (from the Atherosclerosis Risk In Communities Study)
Section snippets
Methods
Data for the present study were from the Atherosclerosis Risk In Communities (ARIC) Study,10 a population-based multicenter prospective study designed to investigate the natural history and cause of atherosclerotic and cardiovascular disease events from 4 US communities in Maryland, Minnesota, Mississippi, and North Carolina (n = 15,792 men and women aged 45 to 64 years). Eligible participants were interviewed at home and then invited to a baseline clinical examination (1987 to 1989). They
Results
Of 13,973 participants, 58% were women and 27% were black (Table 2). Average age of the study group at baseline was 54.4 ± 5.7 years, 33% had hypertension, 11% had diabetes, 4.2% had angina using the Rose questionnaire, 2.1% had left ventricular hypertrophy using Cornell voltage, and 4.2% had major ST-T abnormalities. Statistical analysis of electrocardiographic variables of the study population showed that spatial QRS/T angle was 14° smaller in women (61°) than men (75°), respectively (p
Discussion
Key results from the present investigation from the multivariable-adjusted risk models showed that spatial QRS/T angle was a significant strong independent predictor of incident CHD in women, with an HR of 2.14 (95% confidence interval 1.62 to 2.82), but not a significant predictor of incident CHD in men. Frontal plane QRS/T angle considered separately from spatial QRS/T angle was equally predictive of total mortality and, like spatial QRS/T angle, was predictive of incident CHD in women, but
Acknowledgments
We thank the staff and participants of the ARIC Study for their important contributions.
References (29)
- et al.
Comparison of mortality risk for electrocardiographic abnormalities in men and women with and without coronary heart disease (from the Cardiovascular Health Study)
Am J Cardiol
(2006) - et al.
Spatial QRS-T angle predicts cardiac death in a clinical population
Heart Rhythm
(2005) - et al.
Community surveillance of coronary heart disease in the Atherosclerosis Risk In Communities (ARIC) Study: methods and initial two years’ experience
J Clin Epidemiol
(1996) - et al.
The Novacode criteria for classification of electrocardiographic abnormalities and their clinically significant progression and regression
J Electrocardiol
(1998) - et al.
Vector cardiogram synthesized from a 12-lead ECG: superiority of the inverse Dower matrix
J Electrocardiol
(1988) - et al.
Electrocardiographic detection of left ventricular hypertrophy: development and prospective validation of improved criteria
J Am Coll Cardiol
(1985) - et al.
Waveform vector analysis of orthogonal electrocardiograms: quantification and data reduction
J Electrocardiol
(1973) - et al.
T Axis as an independent indicator of risk of cardiac events in elderly people
Lancet
(1998) - et al.
Usefulness of T-axis deviation as an independent risk indicator for incident cardiac events in older men and women free from coronary heart disease (the Cardiovascular Health Study)
Am J Cardiol
(2001) - et al.
Long-term prognostic significance of isolated minor electrocardiographic T-wave abnormalities in middle aged men free of clinic cardiovascular diseaseThe Multiple Risk Factor Study (MRFIT)
Am J Cardiol
(2002)
Analysis of T wave morphology from the 12-lead electrocardiogram for prediction of long term prognosis in male US veterans
Circulation
Spatial QRS-T angle as a risk indicator of cardiac death in an elderly population
J Electrocardiol
Spatial QRS/T angle predicts cardiac death in a general population
Eur Heart J
The electrical T-axis and the spatial QRS-T angle are independent predictors of long-term mortality in patients admitted with acute ischemic chest pain
Cardiology
Cited by (130)
The effect of coronary slow flow on ventricular repolarization parameters
2023, Journal of ElectrocardiologyWhat can we find in QRS in patients with ST-segment-elevation myocardial infarction?
2022, Journal of ElectrocardiologyFrontal QRS/T angle can predict mortality in COVID-19 patients
2022, American Journal of Emergency MedicinePredictivity of frontal QRS-T angle for death in COVID-19 patients may differ by age
2022, American Journal of Emergency MedicineThe classical 12‑lead ECG: Much more to offer than just a diagnosis in STEMI?
2022, International Journal of Cardiology
The Atherosclerosis Risk In Communities Study is a collaborative study supported by National Heart, Lung, and Blood Institute contracts N01-HC-55015, N01-HC-55016, N01-HC-55018, N01-HC-55019, N01-HC-55020, N01-HC-55021, and N01-HC-55022.