Original articleThe Effect of Systemic Steroids and Orbital Radiation for Active Graves Orbitopathy on Postdecompression Extraocular Muscle Volume
Section snippets
Methods
All patients with GO who underwent orbital 2-wall decompression by 1 surgeon (J.S.Y.) between January 2008 and December 2014 were retrospectively reviewed. The study protocol, which involved a retrospective chart review of all patients meeting the study criteria, was approved by the Institutional Review Board of the Severance Hospital of Yonsei University and adhered to the tenets of the Declaration of Helsinki. All patients provided their written informed consent.
Patients who underwent orbital
Results
A total of 114 clinical charts of patients who underwent orbital wall decompression were reviewed, and 37 patients (73 eyes) fulfilled the inclusion criteria. The ST group consisted of 22 patients (43 eyes) who were administered corticosteroids only, while the SRT group consisted of 15 patients (30 eyes) who underwent OR in addition to corticosteroid treatment. The average age at the time of the operation was 46.65 ± 10.51 years (range: 20–65 years), and 59% (22/37) of the patients were women.
Discussion
This study showed that OR prior to orbital decompression could reduce the postoperative increase in EOM volume as well as the deterioration of diplopia. However, OR had no effect on postoperative changes in proptosis.
Consistent with previous studies, the postoperative volume increased in the total EOMs of the nonradiated orbit by an average of 15% in this study. In a study by Alsuhaibani and associates, a significant increase of 16.5% in the volume of the MR muscle was detected, and a greater
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