Original articleWound Dehiscence as a Cataract Surgery–Associated Postoperative Complication in Patients Previously Treated With Alpha-1 Blocker Tamsulosin—A Population-Based Study in Taiwan
Section snippets
Methods
Taiwan's nationwide National Health Insurance Research Database (NHIRD) was the data source for this retrospective case-control study. We estimated the risk of patients who had undergone cataract surgery with and without preoperative α1-blocker treatment. Taiwan's National Health Insurance program began in 1995, and approximately 99% of the population is currently enrolled in the program.6, 7 Personal information is confidential because patient identification numbers and other sensitive
Results
We identified 23 873 patients who had undergone cataract surgery. After age, sex, and year of surgery matching, we enrolled 8948 patients: 4474 had taken an α1-blocker and 4474 had not. Patients who had taken an α1-blocker lived in areas with a higher level of urbanization and had more hypertension and diabetes mellitus (Table 1).
The number of patients with at least 1 cataract surgery–related complication was not significantly different between the α1-Blocker group (385 [8.61%]) and the No α1
Discussion
We found that the incidence of cataract surgery–related complications was not significantly different between patients who had and had not taken α1-blockers before surgery. The most common cataract surgery–related complications were glaucoma and a dropped nucleus in all groups. Patients who took tamsulosin had 3.81 times more wound dehiscence than did patients who had not taken α1-blockers before surgery.
There are few published articles on cataract surgery–related complications in patients who
Ching-Hsing Hsiao MD, is the director of Ophthalmology in Chi Mei Hospital, Chia Li in Taiwan. He graduated from Chung Shan Medical University and completed his Ophthalmology residency in National Cheng Kung University Hospital,Taiwan. He has interest in cataract and refractive surgery.
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Ching-Hsing Hsiao MD, is the director of Ophthalmology in Chi Mei Hospital, Chia Li in Taiwan. He graduated from Chung Shan Medical University and completed his Ophthalmology residency in National Cheng Kung University Hospital,Taiwan. He has interest in cataract and refractive surgery.