Original articleStudy of Subretinal Exudation and Consequent Changes in Acute Central Serous Chorioretinopathy by Optical Coherence Tomography
Section snippets
Methods
The research protocol and the collection of clinical data and OCT images for this prospective observational cross-sectional study were approved by the ethics committee of the Eye and Ear Nose Throat Hospital, Fudan University (KJ2009-16). Informed consent was obtained from each patient.
In the current study, we enrolled patients with consecutive acute CSC who visited the clinic of Eye and Ear Nose Throat Hospital of Fudan University, Shanghai, between January and June 2013. The clinical
Results
In total, 123 eyes of 123 patients enrolled were studied; 100 of the enrollees were male and 23 were female, 19–76 years of age; the mean age was 42.92 ± 8.87. The mean BCVA (logMAR) was 0.33 ± 0.22 (Snellen 0.47; range, 0.1–1.0) and the mean duration was 24.26 ± 24.41 days (range, 1–90). FA was performed in 48 eyes, showing that each had 1 or several leakage points at the level of the RPE and that 29 eyes presented with typical smokestack dye leaking.
The number, symptom duration and BCVA of
Discussion
Along with localized retinal detachment and RPE abnormalities, in the current study, subretinal exudation, retinal dipping and photoreceptor layer defects were found by OCT in eyes with acute CSC. The locations of the exudation, retinal dipping and photoreceptor layer defects were found, without exception, to be closely related to the site of RPE abnormalities. As indicated by the average symptom duration in the patients with varying OCT findings (Table), the manifestations seemed to occur
Jia Yu is currently a Medical Doctor student of Ophthalmology in Eye and Ear Nose Throat hospital Fudan University Shanghai, China. Her clinical and research interests are retinal disorders and retinal imaging.
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An intelligent location method of key boundary points for assisting the diameter measurement of central serous chorioretinopathy lesion area
2022, Computers in Biology and MedicineCitation Excerpt :As a common macular disease, the effect of CSCR on vision also should not be underestimated. CSCR is characterized by neurosensory retinal detachment (NRD, as shown in Fig. 1) with or without pigment epithelium detachment (PED, as shown in Fig. 14) [5–7], and usually leads to blurred vision, central scotoma, deformed vision and even permanent visual loss in serious cases. Although CSCR is a self-limited ophthalmic disease, that is, some patients can achieve self-healing without any intervention within three to six months, there are still many patients with prolonged course of disease that cannot be autonomously able to reach re-attachment of the neurosensory retina occurring [8].
Weakly supervised detection of central serous chorioretinopathy based on local binary patterns and discrete wavelet transform
2020, Computers in Biology and MedicineCitation Excerpt :In this work, we further apply ML technology and image processing technology to the detection of CSCR in fundus diseases, and carry out detail innovation to improve the detection accuracy of this disease. Many researchers have done clinical studies on CSCR which is caused by the impairment of retinal pigment epithelium (RPE) function due to the increased choroidal permeability, characterized by neurosensory retinal detachment (NRD) with or without pigment epithelium detachment (PED) [5–7], as shown in Fig. 1. The main symptoms of CSCR are blurred vision, decreased vision and deformed vision.
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2019, Progress in Retinal and Eye ResearchCitation Excerpt :However, subretinal hyperreflective dots can also represent plasma proteins from the choriocapillaris and inflammatory debris (Wang et al., 2005). OCT can reveal fibrin clots that result from fibrinogen leaking through a defect in the RPE (Yu et al., 2014). Although changes in choroidal haemodynamics have been observed in aCSC using laser speckle flowgraphy (Saito et al., 2015), subfoveal choroidal thickness does not appear to be correlated with the amount of SRF (Goktas, 2014).
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Jia Yu is currently a Medical Doctor student of Ophthalmology in Eye and Ear Nose Throat hospital Fudan University Shanghai, China. Her clinical and research interests are retinal disorders and retinal imaging.
Chunhui Jiang MD, PhD is a professor in the Department of Ophthalmology at Eye and Ear Nose Thoat hostipal Fudan University Shanghai, China. He got his doctor degree from Fudan University. His clinical and research work mainly focus on retinal imaging by OCT, as well as vitrectomy to treat various vitroretinal entities.