Original articleOptical Coherence Tomography–Guided Transepithelial Phototherapeutic Keratectomy for the Treatment of Anterior Corneal Scarring
Section snippets
Methods
The Southwest Retina Specialists institutional review board (IORG0007600/IRB00009122) approved this retrospective chart review of consecutive cases in patients who underwent OCT-guided transepithelial PTK for anterior corneal scarring between January 2011 and February 2013. All research components adhered to the tenets of the Declaration of Helsinki and were conducted in accordance with human-subject research regulations and standards.
Results
A total of 22 eyes of 20 patients met criteria for inclusion in the study. The various underlying pathologies responsible for the corneal scarring are detailed in Table 1. The mean age of the subjects was 58.6 years (50.4–66.8; 95% CI); 59% were male and 41% female. Table 2 details the pertinent findings of the study. BSCVA (in logMAR) improved from 0.82 (0.61–1.02) to 0.40 (0.19–0.61) (P = 0.0070). The mean baseline epithelial thickness was 51.6 μm, and the mean baseline maximum crater depth
Discussion
Anterior corneal scarring with crater formation presents a significant treatment challenge for the clinician, and currently no consensus exists regarding the best treatment option. The ideal strategy should aim not only to eliminate the corneal opacity but also to improve the overall anatomic shape of the cornea, thereby minimizing postoperative irregular astigmatism and improving BSCVA. The marked distortion and flattening present on corneal topography in patients with anterior corneal
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