Structure
Volume 3, Issue 11, November 1995, Pages 1127-1129
Journal home page for Structure

Minireview
Copper amine oxidase: a novel use for a tyrosine

https://doi.org/10.1016/S0969-2126(01)00247-7Get rights and content
Under an Elsevier user license
open archive

Abstract

The first three-dimensional structure of copper amine oxidase demonstrates that one tyrosine residue is converted into 2,4,5-trihydroxyphenylalanine quinone (TPQ). TPQ binds to copper in the inactive form of the enzyme but not in the active form.

Cited by (0)

Marc Fontecave, Laboratoire d’Etudes Dynamiques et Structurales de la Sélectivité, URA CNRS 332, Université Joseph Fourier, BP 53, 38041 Grenoble Cedex 9, France.

Hans Eklund, Department of Molecular Biology, Swedish University of Agricultural Sciences, Biomedical Center, Box 590, S-751 24 Uppsala, Sweden.