Systems for categorizing functions of gene products
References (28)
- et al.
The complete genome sequence of the gram-positive bacterium Bacillus subtilis
Nature
(1997) - et al.
The complete genome sequence of Escherichia coli K-12
Science
(1997) - et al.
The HSSP database of protein structure-sequence alignments and family profiles
Nucleic Acids Res
(1998) Linkage map of Escherichia K-12, edition 8
Microbiol Rev
(1990)- et al.
Linkage map of Escherichia coli K-12, edition 9
- et al.
Appendix B
Functions of the gene products of E. coli
Microbiol Rev
(1993)- et al.
E. coli gene products: physiological functions and common ancestries
- et al.
EcoCyc: encyclopedia of Escherichia genes and metabolism
Nucleic Acids Res
(1998) Genes and proteins of Escherichia coli K-12 (GenProtEC)
Nucleic Acids Res
(1998)
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
Science
The complete genome sequence of the gastric pathogen Helicobacter pylori
Nature
Protein evolution viewed through Escherichia coli protein sequences: introducing the notion of a structural segment of homology, the module
J Mol Biol
MIPS: a database for protein sequences, complete genomes
Nucleic Acid Res
Cited by (50)
A protet-based, protonic charge transfer model of energy coupling in oxidative and photosynthetic phosphorylation
2021, Advances in Microbial PhysiologyCitation Excerpt :Given that it is in fact highly unlikely that any molecule normally enters undamaged cells by passage through the bilayer (Dobson & Kell, 2008; Kell et al., 2011, 2013; Kell & Oliver, 2014; Winter et al., 2014), this work casts considerable doubt on the likelihood that any permeable ion uptake occurs without any interaction with transporters, and/or the electron transport chain, such that any ‘permeant ion’-based estimates of ‘Δψ’ in energy coupling membranes are (probably major) overestimates. In E. coli, fully one third of the transporters remain ‘y-genes’ (Ghatak et al., 2019), i.e. genes of unknown function (Riley, 1998), and most transporters are not well characterized. From the point of view of determining those transporters that do interact with ‘lipophilic cations’ and related molecules much needs to be done; a similar exercise in yeast (Lanthaler et al., 2011) regularly found as many as six transporters for individual xenobiotics.
New metrics for comparative genomics
2006, Current Opinion in BiotechnologyDefinitions of enzyme function for the structural genomics era
2003, Current Opinion in Chemical BiologyThe Atlas visualization of genomewide information
2002, Methods in MicrobiologyRuleMiner: A knowledge system for supporting high-throughput protein function annotations
2004, Journal of Bioinformatics and Computational Biology