Approach to(R)- and (S)-ketone cyanohydrins using almond and apple meal as the source of (R)-oxynitrilase
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2013, Tetrahedron AsymmetryCitation Excerpt :Therefore, the use of extracts from cassava leaves for (S)-selective HNL, instead of using isolated enzymes is worth noting.11,24 On the other hand, the general use of the volatile and extremely toxic HCN25–36 or acetone cyanohydrins37–40 as cyanide sources in asymmetric cyanohydrination could result in safety concerns. The development of non-volatile cyanide sources is also highly desirable.15,41
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