Polypyrrole electrospotting for the construction of oligonucleotide arrays compatible with a surface plasmon resonance hybridization detection
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Electrochemical DNA sensors based on electropolymerized materials
2012, TalantaCitation Excerpt :The DNA grafting can be performed prior to electrolysis as well. The products of electropolymerization containing DNA probes are suitable not only for voltammetric but also for photovoltaic [133], SPR or fluorescence signal measurements as well [134]. Avidin–biotin binding provides renewal of the biorecognition surface either by solubilization of the avidin or denaturation of the DNA duplex.
Development of a gold nano-particle-based fluorescent molecular beacon for detection of cystic fibrosis associated mutation
2010, Biosensors and BioelectronicsCitation Excerpt :Biosensors and more specifically genosensors are highly valuable platforms in the development of diagnostic tools (Ferguson et al., 1996; Willner, 2002; Teles and Fonseca, 2008). Due to the fact that the physical changes occurring during the recognition event (hybridisation) are small and not easily measurable, highly sensitive transduction approaches are needed, and there are several reports of electrochemical (Wang, 2002; Drummond et al., 2003), gravimetric (Heaton et al., 2001; Livache et al., 2001; Towey et al., 2001) and optical detection (Murphy and Redmond, 2005; Xu and Bard, 1995; Calvo-Munoz et al., 2005; Epstein et al., 2002). Amongst the proposed optical detection tools molecular beacons (MBs) are very attractive.
Effects of formamide on the thermal stability of DNA duplexes on biochips
2010, Analytical BiochemistryArchitectures based on the use of gold nanoparticles and ruthenium complexes as a new route to improve genosensor sensitivity
2008, Biosensors and BioelectronicsElectrochemical kinetic analysis of a 1,4-hydroxynaphthoquinone self-assembled monolayer
2008, Journal of Electroanalytical Chemistry