In this paper, we establish some relationships between vector variational-like inequality and vector optimization problems under the assumptions of α-invex functions. We identify the vector critical points, the weakly efficient points and the solutions of the weak vector variational-like inequality problems, under pseudo-α-invexity assumptions. These conditions are more general than those of existing ones in the literature. In particular, this work extends the earlier work of Ruiz-Garzon et al. [G. Ruiz-Garzon, R. Osuna-Gomez, A. Rufian-Lizan, Relationships between vector variational-like inequality and optimization problems, European J. Oper. Res. 157 (2004) 113–119] to a wider class of functions, namely the pseudo-α-invex functions studied in a recent work of Noor [M.A. Noor, On generalized preinvex functions and monotonicities, J. Inequal. Pure Appl. Math. 5 (2004) 1–9].